Article

Plasma extracellular vesicle Tau isoform ratios and TDP-43 inform about molecular pathology in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

2023-07-13

Abstract excerpt

<title>Abstract</title> <p>Low-invasive biomarkers are urgently needed for the detection of molecular pathology in Frontotemporal Dementia (FTD), FTD spectrum disorders and Amyotrophic Lateral Sclerosis (ALS). This is particularly true in behavior variant FTD (bvFTD), in which <italic>premortem</italic> biomarkers are missing to distinguish underlying Tau from TAR DNA binding protein (TDP-43) pathology. This lack...

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Literature Corpus work: 48a89747-c719-53ef-b4f1-8f23329e9358
DOI: 10.21203/rs.3.rs-3158170/v1

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