Potential therapeutic targets and the role of technology in developing novel antileishmanial drugs.

Abstract excerpt

Leishmaniasis is the most prevalent pathogenic disease in many countries around the world, but there are few drugs available to treat it. Most antileishmanial drugs available are highly toxic, have resistance issues or require hospitalization for their use; therefore, they are not suitable for use in most of the affected countries. Over the past decade, the completion of the genomes of many human pathogens,...

Topics

• Animals
• Computer-Aided Design
• Drug Design
• Drug Discovery
• Drug Resistance
• Genome, Protozoan
• Genomics
• Genotype
• Humans
• Leishmania
• Leishmaniasis
• Molecular Docking Simulation