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Article

Genomic localization bias of secondary metabolite gene clusters and association with histone modifications in <i>Aspergillus</i>

2024-02-22

Abstract excerpt

Fungi are well-known producers of bioactive secondary metabolites (SMs), which have been exploited for decades by humankind for various medical applications like therapeutics and antibiotics. SMs are synthesized by biosynthetic gene clusters (BGCs) – physically co-localized and co-regulated genes. Because BGCs are often regulated by histone post-translational modifications (PTMs), it was suggested that their chrom...

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Literature Corpus work
deb56a4e-2428-5982-8332-ceb8c98dcbcf
DOI
10.1101/2024.02.20.581327
Open publication

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Genomic localization bias of secondary metabolite gene clusters and association with histone modifications in <i>Aspergillus</i>DOI 10.1101/2024.02.20.581327
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