Article
The epigenetic reader SntB regulates secondary metabolism, development and global histone modifications in Aspergillus flavus.
Fungal genetics and biology : FG & B - 1 Nov 2018
Pfannenstiel Brandon T, Greco Claudio, Sukowaty Andrew T, Keller Nancy P
Abstract excerpt
Due to the role, both beneficial and harmful, that fungal secondary metabolites play in society, the study of their regulation is of great importance. Genes for any one secondary metabolite are contiguously arranged in a biosynthetic gene cluster (BGC) and subject to regulation through the remodeling of chromatin. Histone modifying enzymes can place or remove post translational modifications (PTM) on histone...
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