Article

Flawed methods in “COVID-19: Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism”

2020-05-05

Abstract excerpt

This is a critical commentary on an earlier submission by Liu and Li. The preprint from Liu & Li ( https://doi.org/10.26434/chemrxiv.11938173.v7 ) puts forward hypotheses about a proposed role for proteins of SARS-CoV-2, the virus associated with Covid-19, in directly attacking haemoglobin in patients’ blood. Arguments for the hypotheses are based on computational methods: bioinformatics calculations searching fo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: deaa9286-4b2d-5165-b83e-d58b4ae01dd9
DOI: 10.26434/chemrxiv.12120912.v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Flawed methods in “COVID-19: Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism”DOI 10.26434/chemrxiv.12120912.v2Read

SARS-CoV-2 proteins bind heme and hemoglobinSemantic proximity Read

The role of host defences in Covid 19 and treatments thereof.Semantic proximity Read

Atomistic Simulations of Heme Dissociation Pathways in Human Methemoglobins Reveal Hidden Intermediates.Semantic proximity Read

Analysis of functional aberration of some important beta hemoglobinopathies (hemoglobin C, D, E, and S) from nanostructures.Semantic proximity Read

Determinants of hydroxychloroquine-mediated hemolytic anemia in G6PD-deficient COVID-19 patientsSemantic proximity Read

Understanding heme transport.Semantic proximity Read

The evolutionary footprint of histidine in hemoglobin and myoglobin: an implication towards their function.Semantic proximity Read

Synergy of Mutation-Induced Effects in Human Vitamin K Epoxide Reductase: Perspectives and Challenges for Allo-Network Modulator Design.Semantic proximity Read

Computational identification of potential modulators of heme-regulated inhibitor (HRI) for pharmacological intervention against sickle cell diseaseSemantic proximity Read

A computational approach for mapping heme biology in the context of hemolytic disordersSemantic proximity Read

Structural Analysis of Variants of the Ferritin Light Chain Protein and Its Relationship with Neuroferritinopathy.Semantic proximity Read

[Molecular interpretation of the respiratory function of hemoglobin].Semantic proximity Read