Article
ARGX-119, a therapeutic agonist antibody targeting MuSK
2024-07-22
Abstract excerpt
ARGX-119 is a novel, humanized, agonist monoclonal SIMPLE Antibody™ specific for muscle-specific kinase (MuSK) that is being developed for treatment of patients with neuromuscular diseases. ARGX-119 is the first monoclonal antibody (mAb) that binds with high affinity to the Frizzled-like domain of human, non-human primate, rat and mouse MuSK, without off-target binding, making it suitable for clinical development....
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Identifiers and source
- Literature Corpus work
- de81ccf1-2de7-5295-96b1-1b31649108a2
- DOI
- 10.1101/2024.07.18.604166
