Article

A HUMANIZED FCRN TRANSGENIC MOUSE FOR PRECLINICAL PHARMACOKINETICS STUDIES

2022-10-25

Abstract excerpt

<h4>ABSTRACT</h4> Monoclonal antibodies (mAbs) are one of the fastest-growing classes of drugs and have been approved to treat several diseases, including cancers and autoimmune disorders. Preclinical pharmacokinetics studies are performed to determine the therapeutically meaningful dosages and efficacy of candidate drugs. These studies are typically performed in non-human primates; however, using primates is cos...

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Literature Corpus work: 0d971c69-0764-5d87-a7e6-1fb59287f278
DOI: 10.1101/2022.10.24.513622

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