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Article

Dok-7/MuSK signaling and a congenital myasthenic syndrome.

Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology - 1 Jul 2008

Yamanashi Y, Higuch O, Beeson D

Abstract excerpt

Skeletal muscle contraction is controlled by motor neurons, which contact the muscle at the neuromuscular junction (NMJ). The formation and maintenance of the NMJ, which includes the aggregation of densely packed clusters of acetylcholine receptor (AChR) opposite the motor nerve terminal, is orchestrated by muscle-specific receptor tyrosine kinase, MuSK. Recently, a MuSK-interacting cytoplasmic adaptor-like...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle, Skeletal

Share to Myasthenic Syndromes, Congenital

Share to Neuromuscular Junction

Share to Receptor Protein-Tyrosine Kinases

Share to Receptors, Cholinergic

Source

Open in PubMed Open full text

Identifiers

PMID: 19108574
PMCID: PMC2859609

Genes

DOK7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Dok-7/MuSK signaling and a congenital myasthenic syndrome.PMID 19108574Read ↗

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The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization.Semantic proximity Read ↗

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