From Sequence to Salvation: Delivering on the Promise of Precision Medicine in Childhood Cancer

Abstract excerpt

Whole genome sequencing not only changed how we codify pediatric cancers but also opened the door to extraordinary treatment therapies. However, for most of patients, genetic results guide real treatments difficultly. Large studies show that about 30–50% of children with cancer have at least one genetic change treated with a precision therapy, but only 5–10% actually receive such treatment, and long-term advantage...

Topics

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• BRCA gene mutations in cancer
• Child
• Childhood Cancer Survivors' Quality of Life
• Genomics
• High-Throughput Nucleotide Sequencing
• Mutation
• Neoplasms
• Precision Medicine

Identifiers and source

Literature Corpus work

de7f84e1-35ee-59d9-a1e4-2e8608039f4a

DOI

10.22541/au.176371037.70777032/v1