Article

Myeloid-Mediated Immunoregulation Across Squamous Cell Carcinomas

2026-07-15

Abstract excerpt

Immune checkpoint inhibitors (ICIs) targeting PD-1/PD-L1 have improved outcomes across squamous cell carcinomas (SCCs) of the head and neck, lung, esophagus, and skin, yet durable responses remain confined to a subset of patients in every subtype. Objective response rates vary substantially across SCCs despite overlapping genomic alterations, comparable tumor mutational burden, and high PD-L1 expression, indicatin...

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Literature Corpus work: de7d931b-e910-55e9-9db4-74795654dd7c
DOI: 10.20944/preprints202607.1129.v1

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