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Single-cell sequencing reveals tumor microenvironment features associated with the response to neoadjuvant immunochemotherapy in oral squamous cell carcinoma

19 Mar 2025

Abstract excerpt

OBJECTIVES: In recent years, immune checkpoint inhibitors have shown promise as neoadjuvant therapies in the treatment of locally advanced oral squamous cell carcinoma (OSCC). However, the factors affecting the tumor response to immune checkpoint inhibitors (ICIs) remain unclear. This study aimed to analyze the impact of neoadjuvant chemoimmunotherapy (NACI) on the tumor microenvironment of OSCC via single-cell...

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PMID: 40105941
DOI: 10.1007/s00262-025-04014-2

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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