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LINCS gene expression signatures analysis revealed bosutinib as a radiosensitizer of breast cancer cells by targeting <i>eIF4G1</i>

2020-04-24

Abstract excerpt

Radioresistance represents the predominant cause for radiotherapy failure and disease progression, resulting in increased breast cancer mortality. Through gene expression signatures analyses of Library of Integrated Network-Based Cellular Signatures (LINCS) and Gene Expression Omnibus (GEO), the present study aimed to identify potential candidate radiosensitizers from known drugs systematically. The similarity of...

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Literature Corpus work
de7b14a3-958f-5b10-bfae-f3d580bb400a
DOI
10.1101/2020.04.24.059378
Open publication

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LINCS gene expression signatures analysis revealed bosutinib as a radiosensitizer of breast cancer cells by targeting <i>eIF4G1</i>DOI 10.1101/2020.04.24.059378
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