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Article

Development and Validation of a Novel Radiosensitivity Signature in Human Breast Cancer

22 Apr 2015

Abstract excerpt

PURPOSE: An unmet clinical need in breast cancer management is the accurate identification of patients who will benefit from adjuvant radiotherapy. We hypothesized that integration of postradiation clonogenic survival data with gene expression data across breast cancer cell (BCC) lines would generate a radiation sensitivity signature (RSS) and identify patients with tumors refractive to conventional therapy....

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Identifiers

PMID: 25904749
DOI: 10.1158/1078-0432.ccr-14-2898

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