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Genetic and transcriptomic determinants of disseminated coccidioidomycosis identify a founder variant in <i>NLRX1</i> and ancestry-specific rare variants in immune response genes

2026-06-30

Abstract excerpt

<h4>ABSTRACT</h4> Coccidioidomycosis, also known as Valley Fever, is a fungal disease endemic to the Americas that kills hundreds annually, yet the host factors that lead to increased risk of life-threatening dissemination of coccidioidomycosis remain poorly understood. We assembled the largest comprehensively sequenced coccidioidomycosis cohort to date, comprising 795 individuals with laboratory confirmed coccid...

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Literature Corpus work
3f97cc87-dbf8-5a66-a410-d487fbcecbed
DOI
10.64898/2026.06.26.26356412
Open publication

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Genetic and transcriptomic determinants of disseminated coccidioidomycosis identify a founder variant in <i>NLRX1</i> and ancestry-specific rare variants in immune response genesDOI 10.64898/2026.06.26.26356412
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