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Article

Genome-wide association analyses of common infections in a large practice-based biobank.

BMC genomics - 27 Sept 2022

Jiang Lan, Kerchberger V Eric, Shaffer Christian, Dickson Alyson L, Ormseth Michelle J, Daniel Laura L, Leon Barbara G Carranza, Cox Nancy J, Chung Cecilia P, Wei Wei-Qi, Stein C Michael, Feng QiPing

Abstract excerpt

INTRODUCTION: Infectious diseases are common causes of morbidity and mortality worldwide. Susceptibility to infection is highly heritable; however, little has been done to identify the genetic determinants underlying common infectious diseases. One GWAS was performed using 23andMe information about self-reported infections; we set out to confirm previous loci and identify new ones using medically diagnosed...

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Identifiers

PMID: 36167494
DOI: 10.1186/s12864-022-08888-9
PMCID: PMC9512962

Genes

AAMDC
LRP3
SLC30A9

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