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Strand-biased circularizing integrative elements spread <i>tmexCD-toprJ</i> gene clusters encoding RND-type multidrug efflux pumps by repeated transpositions

2022-09-22

Abstract excerpt

Antimicrobial resistance genes (ARGs) are associated with mobile genetic elements (MGEs) that conscript useful genes into the human–microbe and microbe–microbe battlefields. Thus, under intense selective pressure, ARGs have been constantly adapting and evolving, spreading among microbes. tmexCD-toprJ gene clusters, which encode resistance–nodulation–cell division (RND)-type efflux pumps, confer multidrug-resistan...

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Literature Corpus work
de69503b-8055-5026-827e-64f050d54032
DOI
10.1101/2022.09.22.508988
Open publication

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Strand-biased circularizing integrative elements spread <i>tmexCD-toprJ</i> gene clusters encoding RND-type multidrug efflux pumps by repeated transpositionsDOI 10.1101/2022.09.22.508988
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