Article

Emergence of a novel mobile RND-type efflux pump gene cluster, <i>tmexC3D2-toprJ1b</i> , in <i>Pseudomonas</i> species

2021-07-27

Abstract excerpt

Tigecycline exhibits promising activity against multidrug-resistant Gram-negative bacteria (MDR-GNB), whose infections are difficult to treat with antimicrobials. However, mobile tigecycline resistance genes, such as tmexCD-toprJ , have emerged in Enterobacterales isolated in China, Vietnam, and possibly other countries in the world. In this study, we investigated tigecycline-nonsusceptible GNB in Japan. Eight ti...

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Literature Corpus work: 587fd574-18fd-59e3-881d-0368ce221dd8
DOI: 10.1101/2021.07.26.453812

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