Article

Post-infectious inflammatory disease in MIS-C features elevated cytotoxicity signatures and autoreactivity that correlates with severity

2020-12-04

Abstract excerpt

<h4>SUMMARY</h4> Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening post-infectious complication occurring unpredictably weeks after mild or asymptomatic SARS-CoV2 infection in otherwise healthy children. Here, we define immune abnormalities in MIS-C compared to adult COVID-19 and pediatric/adult healthy controls using single-cell RNA sequencing, antigen receptor repertoire analysis, unbi...

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Literature Corpus work: de520cd4-8c03-5fb7-9c5c-d1e54ccffa77
DOI: 10.1101/2020.12.01.20241364

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