Article

Multiplatform Analyses Reveal Distinct Drivers of Systemic Pathogenesis in Adult Versus Pediatric COVID-19

2022-01-12

Abstract excerpt

The pathogenesis of the multi-organ dysfunction associated with severe COVID-19 remains poorly understood. Endothelial dysfunction has been identified as a driver of severity in SARS-CoV-2-infections, yet the mechanisms underlying this endotheliopathy remain elusive. We performed proteomics, lipidomics and metabolomics using plasma from severely ill COVID adults, controls and children with acute COVID-19 or multis...

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Literature Corpus work: 95a824d4-a8a3-568c-a392-53b4d1025d23
DOI: 10.2139/ssrn.4007576

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