Multisystem Inflammatory Syndrome of Children: Subphenotypes, Risk Factors, Biomarkers, Cytokine Profiles, and Viral Sequencing.

doi:10.1016/j.jpeds.2021.06.002

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Article

Multisystem Inflammatory Syndrome of Children: Subphenotypes, Risk Factors, Biomarkers, Cytokine Profiles, and Viral Sequencing.

The Journal of pediatrics - 1 Oct 2021

DeBiasi Roberta L, Harahsheh Ashraf S, Srinivasalu Hemalatha, Krishnan Anita, Sharron Matthew P, Parikh Kavita, Smith Karen, Bell Michael, Michael Drew, Delaney Meghan, Campos Joseph, Vilain Eric, LoTempio Jonathan, Kline Jaclyn N, Ronis Tova, Majumdar Suvankar, Sadler Eleanor, Conway Susan R, Berul Charles I, Sule Sangeeta, Lahoz Rebeca, Ansusinha Emily, Pershad Jay, Bundy Vanessa, Wells Elizabeth, Bost James E, Wessel David

Abstract excerpt

OBJECTIVE: To assess demographic, clinical, and biomarker features distinguishing patients with multisystem inflammatory syndrome in children (MIS-C); compare MIS-C sub-phenotypes; identify cytokine biosignatures; and characterize viral genome sequences. STUDY DESIGN: We performed a prospective observational cohort study of 124 children hospitalized and treated under the institutional MIS-C Task Force protocol...

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PMID: 34181987
DOI: 10.1016/j.jpeds.2021.06.002

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