Article

Targeting TRIP13 in Wilms Tumor with Nuclear Export Inhibitors

2022-02-25

Abstract excerpt

<h4>ABSTRACT</h4> Wilms tumor (WT) is the most common renal malignancy of childhood. Despite improvements in the overall survival, relapse occurs in ~15% of patients with favorable histology WT (FHWT). Half of these patients will succumb to their disease. Identifying novel targeted therapies in a systematic manner remains challenging in part due to the lack of faithful preclinical in vitro models. We established...

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Literature Corpus work: de19b1e8-5678-51fa-ba0a-cf2d0401d0f9
DOI: 10.1101/2022.02.23.481521

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