Article

Lysosomal-associated protein transmembrane 5 ameliorates non-alcoholic steatohepatitis through degradating CDC42

2022-09-23

Abstract excerpt

<title>Abstract</title> <p>Non-alcoholic steatohepatitis (NASH) has received great attention due to its extremely high incidence. Our team screened LAPTM5 associated with NASH progression through extensive bioinformatics analysis. We found protein LAPTM5 markedly decreased in response to lipotoxicity both in liver tissues from human and mouse NASH groups, and protein level of LAPTM5 was negatively correlated with...

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Literature Corpus work: ddf0405a-467c-5d28-9b7a-20696b4bc7cb
DOI: 10.21203/rs.3.rs-2065929/v1

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