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Self-transfecting GMO-PMO and PMO-GMO chimeras enable gene silencing <i>in vitro and in vivo</i> zebrafish model and NANOG Inhibition Induce the Apoptosis in Breast and Prostate Cancer Cells

2021-06-04

Abstract excerpt

Phosphorodiamidate Morpholino Oligonucleotides (PMOs)-based antisense reagents cannot enter inside cells by itself without the help of any delivery technique which is the last hurdle for their clinical applications. To overcome this limitation, a self-transfecting GMO-PMO or PMO-GMO chimeras has been explored as a gene silencing reagent where GMO stands for guanidinium morpholino oligonucleotides which linked eith...

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Literature Corpus work
ddc825ad-60db-5e0a-9c39-cc53246ddea4
DOI
10.1101/2021.06.04.447039
Open publication

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Self-transfecting GMO-PMO and PMO-GMO chimeras enable gene silencing <i>in vitro and in vivo</i> zebrafish model and NANOG Inhibition Induce the Apoptosis in Breast and Prostate Cancer CellsDOI 10.1101/2021.06.04.447039
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