Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vivo-Morpholinos: a non-peptide transporter delivers Morpholinos into a wide array of mouse tissues.

BioTechniques - 1 Dec 2008

Morcos Paul A, Li Yongfu, Jiang Shan

Abstract excerpt

We have developed a new transporter structure that provides effective delivery of Morpholino antisense oligomers into a wide variety of tissues in living mice. This transporter comprises a dendritic structure assembled around a triazine core which serves to position eight guanidinium head groups...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Delivery Systems
Share to Dystrophin
Share to Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanidine

Share to Mice, Inbred mdx

Share to Muscular Dystrophy, Duchenne

Share to Oligonucleotides, Antisense

Share to Triazines

Source

Identifiers

PMID: 19238792
DOI: 10.2144/000113005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19238792-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vivo-Morpholinos: a non-peptide transporter delivers Morpholinos into a wide array of mouse tissues.PMID 19238792Read ↗

Heteroduplex oligonucleotide technology boosts oligonucleotide splice switching activity of morpholino oligomers in a Duchenne muscular dystrophy mouse modelSemantic proximity Read ↗

Morpholino oligomer-mediated exon skipping averts the onset of dystrophic pathology in the mdx mouse.Semantic proximity Read ↗

Rapid and scalable preclinical evaluation of personalized antisense oligonucleotide therapeutics using organoids derived from rare disease patientsSemantic proximity Read ↗

Thiomorpholino oligonucleotides as a robust class of next generation platforms for alternate mRNA splicingSemantic proximity Read ↗

Targeting nuclear RNA for in vivo correction of myotonic dystrophy.Semantic proximity Read ↗

Identification and Characterization of Modified Antisense Oligonucleotides Targeting DMPK in Mice and Nonhuman Primates for the Treatment of Myotonic Dystrophy Type 1Semantic proximity Read ↗

Systemic Delivery of Morpholinos to Skip Multiple Exons in a Dog Model of Duchenne Muscular Dystrophy.Semantic proximity Read ↗

Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomerSemantic proximity Read ↗

Application of Antisense Conjugates for the Treatment of Myotonic Dystrophy Type 1Semantic proximity Read ↗

High-throughput discovery of arginine-depleted peptides enables effective antisense delivery for Duchenne muscular dystrophySemantic proximity Read ↗

DG9-conjugated morpholino rescues phenotype in SMA mice by reaching the CNS via a subcutaneous administration.Semantic proximity Read ↗

Systemic delivery of a Peptide-linked morpholino oligonucleotide neutralizes mutant RNA toxicity in a mouse model of myotonic dystrophy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.