Article

High-Dose-Androgen-Induced Autophagic Cell Death to Suppress the Enzalutamide-Resistant Prostate Cancer Growth Via Altering the circRNA-BCL2/miRNA-198/AMBRA1 Signaling

2021-11-10

Abstract excerpt

<h4>Background: </h4> Androgen deprivation therapy (ADT) is a gold standard treatment for advanced PCa. However, most patients eventually develop the castration-resistant prostate cancer (CRPC) that progresses rapidly despite ongoing systemic androgen deprivation. While early studies indicated that high physiological doses of androgens might suppress rather than promote PCa cell growth in some selective CRPC patie...

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Literature Corpus work: dd99ea5c-bfd7-53ba-8065-c56efe4258d1
DOI: 10.21203/rs.3.rs-957513/v1

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