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The endothelial scavenger receptor <i>stab2</i> is required for proper hematopoietic stem and progenitor cell development in the fetal blood stem cell niche

2026-07-08

Abstract excerpt

Hematopoietic stem and progenitor cell (HSPC) niches support lifelong production of blood and immune cells. Recently, we identified a gene signature unique to HSPC niche endothelial cells that is highly conserved across species and developmental time and includes the scavenger receptors stab1/2 and mrc1a . Whether these receptors support HSPC development remains unclear. To investigate this, we used chemical inh...

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Literature Corpus work
dd7aac49-910a-58e7-a09e-5d4c00a5d218
DOI
10.64898/2026.07.07.737122
Open publication

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The endothelial scavenger receptor <i>stab2</i> is required for proper hematopoietic stem and progenitor cell development in the fetal blood stem cell nicheDOI 10.64898/2026.07.07.737122
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