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Article

Pannexin 1 and Pannexin 3 differentially regulate the tumorigenic properties of cutaneous squamous cell carcinoma

2024-04-11

Abstract excerpt

Pannexin (PANX) channels are present in skin and facilitate the movement of signalling molecules during cellular communication. PANX1 and PANX3 function in skin homeostasis and keratinocyte differentiation but were previously reduced in a small cohort of human cutaneous squamous cell carcinoma (cSCC) tumours compared to normal epidermis. In our study, we used SCC-13 cells, limited publicly available RNA-seq data a...

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Identifiers and source

Literature Corpus work
dd5fb000-3033-580e-9cf6-a7319eaab1c0
DOI
10.1101/2024.04.08.588550
Open publication

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Pannexin 1 and Pannexin 3 differentially regulate the tumorigenic properties of cutaneous squamous cell carcinomaDOI 10.1101/2024.04.08.588550
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