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Article

WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma

13 Apr 2018

Abstract excerpt

Human papillomavirus (HPV)-driven cutaneous squamous cell carcinoma (cSCC) is the most common cancer in immunosuppressed patients. Despite indications suggesting that HPV promotes genomic instability during cSCC development, the molecular pathways underpinning HPV-driven cSCC development remain unknown. We compared the transcriptome of HPV-driven mouse cSCC with normal skin and observed higher amounts of...

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PMID: 29662191
DOI: 10.1038/s41388-018-0244-x

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