Article

The human Flower isoform hFWE4 facilitates cornification in cutaneous squamous cell carcinoma

2025-09-12

Abstract excerpt

<h4>ABSTRACT</h4> Cutaneous squamous cell carcinoma (cSCC) is the second most common human tumor and arises from keratinocytes that comprise the epidermis and its associated hair follicles. Remarkably, transformed keratinocytes within a cSCC retain some ability to execute the terminal differentiation program that typically generates a stratified epidermis. Instead of the polarized stratification towards the body...

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Literature Corpus work: cede4ea4-7f27-5f44-985c-569a7f93ad8f
DOI: 10.1101/2025.09.10.671985

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