Article

Heterogeneity in the gene regulatory landscape of leiomyosarcoma

2022-04-14

Abstract excerpt

Soft-tissue sarcomas are group of rare, tremendously heterogeneous, and highly aggressive malignancies. Characterizing inter-tumor heterogeneity is crucial for selecting suitable sarcoma therapy, as the presence of diverse molecular subgroups of patients can be associated with disease outcome or response to treatment. While cancer subtypes are often characterized by differences in gene expression, the mechanisms t...

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Literature Corpus work: dd57b195-91a2-5d86-b19f-d9741cf3ae21
DOI: 10.1101/2022.04.13.488196

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