Article

Integrative transcriptomics analysis for uterine leiomyosarcoma identifies aberrant activation of cell cycle-dependent kinases and their potential therapeutic significance

2022-01-07

Abstract excerpt

<h4>Purpose</h4> Uterine leiomyosarcoma is among the most aggressive gynecological malignancies. No effective treatment strategies have been established. This study aimed to identify novel therapeutic targets for uterine leiomyosarcoma based on transcriptome analysis and assess the preclinical efficacy of novel drug candidates. <h4>Experimental Design</h4> Transcriptome analysis was carried out using fresh-frozen...

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Literature Corpus work: d137578e-5f69-5c52-9a18-618fe127058e
DOI: 10.1101/2022.01.06.22268775

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