Article

Simulation of cancer cell line pharmacogenomics data to optimise experimental design and analysis strategy

2018-11-13

Abstract excerpt

Explaining the variability in drug sensitivity across a panel of cell lines using genomic information is a key aspect of cancer drug discovery. The results of such analyses may ultimately determine which patients are likely to benefit from a new treatment. There are numerous experimental factors that can influence the outcomes of cell line screening panels such as the number of replicates, number of doses explored...

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Identifiers and source

Literature Corpus work: d72047ce-5c06-51e3-a95b-f33ab33305ed
DOI: 10.7287/peerj.preprints.27345v1

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