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The role of connective tissue growth factor (CTGF) in articular cartilage

2015-01-01

Abstract excerpt

Work from our group has identified an important role for the pericellular matrix (PCM) of cartilage in mechanotransduction. This region of the matrix sequesters regulatory molecules such as fibroblastic growth factor 2 (FGF2) and releases them upon mechanical stimulation. By carrying out a proteomic analysis of PCM proteins we identified an additional regulatory molecule, connective tissue growth factor (CTGF). CT...

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Literature Corpus work
dd200b24-461f-57c5-a588-7c5a15a0e6d5
DOI
10.25560/25292
Open publication

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