Article

Protein Translation Dysregulation and Immune Cell Evasion Define Metastatic Clones in HPV-related Cancer of the Oropharynx

2024-04-18

Abstract excerpt

<h4>Summary</h4> Head and neck cancers, representing the seventh most common malignancy globally, have seen a shift in causative factors from traditional smoking and alcohol use to human papillomavirus (HPV) infection, now accounting for up to 80% of oropharyngeal cancers. We identify the cellular and clonal mechanisms underlying immune avoidance and metastasis by analysing single-cell and spatial genomic data fr...

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Literature Corpus work: dd1ae0d8-2876-5f8c-b63c-ab532a2d1446
DOI: 10.1101/2024.04.15.589624

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