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Article

Dual prognostic role for 2-oxoglutarate oxygenases in ten diverse cancer types: Implications for cell cycle regulation and cell adhesion maintenance

2018-10-14

Abstract excerpt

<h4>Objectives</h4> Tumor hypoxia is associated with metastasis and resistance to chemotherapy and radiotherapy. Genes involved in oxygen-sensing are clinically relevant and have significant implications on prognosis. <h4>Methods</h4> We identified of two signatures, signature 1 (good prognosis) and signature 2 (adverse prognosis), each consisting of 5 genes using three pancreatic cancer cohorts (n=681). We vali...

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Literature Corpus work
1fee3ee5-e633-5b82-8753-ee5cb7388a00
DOI
10.1101/442947
Open publication

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Dual prognostic role for 2-oxoglutarate oxygenases in ten diverse cancer types: Implications for cell cycle regulation and cell adhesion maintenanceDOI 10.1101/442947
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