Back to search

Article

TyG Index Trajectories and Cardiometabolic Outcomes Across the Lifespan: A Dual-Cohort Study Integrating Pediatric Latent Profile Analysis with Adult Longitudinal Validation

2026-08-03

Abstract excerpt

<title>Abstract</title> <p>Background The triglyceride-glucose (TyG) index is a well-established surrogate marker of insulin resistance, yet its transition from childhood metabolic phenotypes to adult trajectories and their joint association with metabolic dysfunction-associated steatotic liver disease (MASLD) and cardiometabolic outcomes remains poorly characterized. Methods We conducted a dual-cohort study in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
dcfea844-fb4f-54ce-b169-4d7fc0192324
DOI
10.21203/rs.3.rs-10443438/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
TyG Index Trajectories and Cardiometabolic Outcomes Across the Lifespan: A Dual-Cohort Study Integrating Pediatric Latent Profile Analysis with Adult Longitudinal ValidationDOI 10.21203/rs.3.rs-10443438/v1
Proteomic signatures of pediatric cardiovascular and cardiometabolic traits demonstrate long-term modifiable drivers of adult diseaseSemantic proximity
Longitudinal Variability of Lipoprotein(a) in Children with Type 1 Diabetes: Implications for Cardiovascular Risk StratificationSemantic proximity
The triglyceride glucose index trajectory is associated with hypertension: a retrospective longitudinal cohort studySemantic proximity
Metabolic Risk Factors in NonCVD Individuals and Their Trajectory Toward Cardiovascular IncidenceSemantic proximity
Triglyceride-glucose indices distinguish clinical from preclinical obesity in US adults: A cross-sectional study.Semantic proximity
Impact of surrogates for insulin resistance on mortality and life expectancy in primary care: a nationwide cross-sectional study with registry linkage (LIPIDOGRAM2015)Semantic proximity
Biochemical and Inflammatory Profiles in Paediatric Obesity, Undernutrition and Normal Weight: A Single-Centre Retrospective Cohort StudySemantic proximity
Association of accelerated phenotypic aging, lifestyle and genetic risk with progression of cardiometabolic multimorbidity: a multi-state model analysis.Semantic proximity
Association of longitudinal body mass index trajectories with phenotypic age acceleration: a cross-sectional study based on growth mixture modeling.Semantic proximity
Telomere length as a biomarker of early cumulative burden of metabolic syndrome components.Semantic proximity
Phenotypic Heterogeneity of Obesity and Short-Term Cardiometabolic Risk Factors Transitions: A Population-Based Cohort Study.Semantic proximity
Metabolically obese normal weight phenotype in children and adolescents aged 3 to 18 years: a systematic review.Semantic proximity
Select a neighboring publication to make it the new centre.