Waist-to-height ratio as a practical indicator for screening pediatric metabolic dysfunction-associated steatotic liver disease in diverse populations and genetic backgrounds.

doi:10.1007/s12519-026-01084-9

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Article

Waist-to-height ratio as a practical indicator for screening pediatric metabolic dysfunction-associated steatotic liver disease in diverse populations and genetic backgrounds.

World journal of pediatrics : WJP - 1 Jul 2026

Liu Yun-Fei, Wang You-Xin, Li Li, Shi Di, Wolters Maike, Zhang Ping-Ping, Dang Jia-Jia, Cai Shan, Huang Tian-Yu, Wang Ya-Qi, Liu Jie-Yu, Wang Ming-Yue, Wu Yu-Ying, Nur Enkar, Lian Wen-Jia, Guo Li-Po, Li Yuan-Yuan, Song Jie-Yun, Li Jing, Dong Yan-Hui, Cui Yan-Chun, Hebestreit Antje, Yeo Yee Hui, Sawyer Susan M, Wang Hui, Song Yi

Abstract excerpt

BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the leading chronic liver disease in children and adolescents; this parallels the global obesity epidemic. The contribution of genetic susceptibility to pediatric MASLD, and its interaction with anthropometric and biochemical indices used for non-invasive screening remains poorly understood. We aimed to evaluate waist-to-height ratio...

Read the complete abstract on PubMed

Topics

Humans
Child
Female
Waist-Height Ratio

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Genetic Predisposition to Disease

Adolescent

Fatty Liver

Polymorphism, Single Nucleotide

China

Mass Screening

Genetic Risk Score

Nutrition Surveys

Source

Open in PubMed

Identifiers

PMID: 42663907
DOI: 10.1007/s12519-026-01084-9

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