Article
Bile Acid Regulates the Colonization and Dissemination of <i>Candida albicans</i> from the Gastrointestinal Tract by Controlling Host Defense System and Microbiota
2021-09-30
Abstract excerpt
Candida albicans ( CA ), a commensal and opportunistic eukaryotic organism, frequently inhabits the gastrointestinal (GI) tract and causes life-threatening infections. Antibiotic-induced gut dysbiosis is a major risk factor for increased CA colonization and dissemination from the GI tract. We identified a significant increase of taurocholic acid (TCA), a major bile acid in antibiotic-treated mice susceptible to...
Topics
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- Alcohol Consumption and Health Effects
- Antifungal resistance and susceptibility
- Clostridium difficile and Clostridium perfringens research
- Digestive system and related health
- Drug Transport and Resistance Mechanisms
- Gastrointestinal motility and disorders
- Gut microbiota and health
- Probiotics and Fermented Foods
Identifiers and source
- Literature Corpus work
- 34df169e-16b5-5da0-86cc-64946d81b190
- DOI
- 10.1101/2021.09.29.462497
