Article

SHMT2 arginine methylation by PRMT1 facilitates esophageal cancer progression by enhancing glycolysis and one-carbon metabolism

2025-01-02

Abstract excerpt

<title>Abstract</title> <p> Background Protein arginine methyltransferase 1 (PRMT1) is the main enzyme that directly responsible for the production of asymmetric dimethylarginine (ADMA), and upregulation of PRMT1 is observed in a variety of malignancies, including esophageal cancer (ESCA). Dysregulation of arginine methylation caused by PRMT1 overexpression is a driver of poor cancer progression, and the detail...

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Literature Corpus work: 09c37ec7-2534-557a-ad26-2c8a2fd5512b
DOI: 10.21203/rs.3.rs-3291514/v2

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