Article

Phenotype-based screening of synthetic cannabinoids in a Dravet Syndrome zebrafish model

2019-10-23

Abstract excerpt

Dravet syndrome (DS) is a catastrophic epilepsy of childhood, characterized by cognitive impairment, severe seizures and increased risk for sudden unexplained death in epilepsy (SUDEP). Although refractory to conventional antiepileptic drugs, emerging preclinical and clinical evidence suggests that modulation of the endocanniboid system could be therapeutic in these patients. Here we used a validated zebrafish mod...

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Literature Corpus work: dce085a6-b8d1-52aa-a84c-5eb17b55828a
DOI: 10.1101/815811

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