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Article

Effects of hydroxychloroquine on atrial electrophysiology in in silico wild-type and PITX2+/- atrial cardiomyocytes

2022-12-11

Abstract excerpt

Hydroxychloroquine (HCQ) is commonly used in the treatment of autoimmune diseases and increases the risk of QT interval prolongation. We quantitatively examined the potential atrial arrhythmogenic effects of HCQ on atrial fibrillation (AF) using a computational model of human atrial cardiomyocytes. We measured atrial electrophysiological markers after systematically varying HCQ concentrations. HCQ concentrations w...

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Identifiers and source

Literature Corpus work
dcccedf6-eefc-5c56-bbcb-fea25d137204
DOI
10.1101/2022.12.07.519115
Open publication

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Effects of hydroxychloroquine on atrial electrophysiology in in silico wild-type and PITX2+/- atrial cardiomyocytesDOI 10.1101/2022.12.07.519115
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