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Article

Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication

25 Nov 2015

Abstract excerpt

BACKGROUND & AIMS: Yearly, approximately 20million people become infected with the hepatitis E virus (HEV) resulting in over 3million cases of acute hepatitis. Although HEV-mediated hepatitis is usually self-limiting, severe cases of fulminant hepatitis as well as chronic infections have been reported, resulting annually in an estimated 60,000 deaths. We studied whether pluripotent stem cell (PSC)-derived...

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PMID: 26626494
DOI: 10.1016/j.jhep.2015.11.013

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