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Plasma miRNA Biomarker Signatures in Parkinsonian Syndromes

4 Apr 2025

Abstract excerpt

Diagnosing atypical parkinsonian syndromes (APS) remains challenging due to overlapping clinical features and limited diagnostic tools. Brain-enriched microRNAs (miRNAs), which regulate neuronal development and function, are detectable in plasma and could serve as molecular biomarkers. This prospective study aimed to identify plasma brain-enriched miRNAs that can distinguish APS and elucidate affected molecular...

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PMID: 40184025
DOI: 10.1007/s12035-025-04890-w

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