Article

New triazole triterpene derivative exhibits anti-RSV activity synthesis biological evaluation and molecular modeling

2022-04-29

Abstract excerpt

Respiratory syncytial virus (RSV) is a major cause of acute lower respiratory tract infections in infants. Currently, ribavirin, a nucleoside analog containing 1,2,4-triazole-3-carboxamide moiety, is a first-line drug for its treatment, however, its clinical use has been limited due to its side effects. Here, we designed a new aryl-nitro-1,2,3-triazole triterpenes derivatives as novel anti-RSV drugs. Their anti-RS...

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Literature Corpus work: dc9b38e2-1283-533e-b091-8fbab3c2ae1d
DOI: 10.3762/bxiv.2022.31.v1

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