Article

The loss of DLG2 isoform 7/8, but not isoform 2, is critical in advanced staged neuroblastoma

2021-02-02

Abstract excerpt

<title>Abstract</title> <p>BACKGROUND:Neuroblastoma is a childhood neural crest tumor showing large clinical and genetic heterogeneity, one form displaying 11q-deletion is very aggressive. It has been shown that 11q-deletion results in decreased expression of <italic>DLG2</italic>, a gene residing in the deleted region. <italic>DLG2</italic> has a number of different isoforms with the main difference is the prese...

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Literature Corpus work: dc618519-2bb4-53a6-b37d-0a505fe3f556
DOI: 10.21203/rs.3.rs-92632/v2

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