Article

Targeting GABARAPL1/HIF-2a in nasopharyngeal carcinoma

2023-04-18

Abstract excerpt

The primary gene mutations associated with nasopharyngeal carcinoma (NPC) are located within phosphoinositide 3-kinase (PI3K)-mammalian target of rapamycin (mTOR) signaling pathways. These pathways have inhibitory effects on autophagy, and autophagy has become an important area of NPC research. However, the potential molecular targets related to autophagy in NPC remain to be elucidated. The current study examined...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dc2aaa4f-4713-5f07-b279-c81f1229a1b8
DOI: 10.21203/rs.3.rs-2817362/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Targeting GABARAPL1/HIF-2a in nasopharyngeal carcinomaDOI 10.21203/rs.3.rs-2817362/v1Read

The Multifaceted Role of Autophagy in Nasopharyngeal Carcinoma: Translational Perspectives on Pathogenesis, Biomarkers, Treatment Resistance, and Emerging TherapiesSemantic proximity Read

lncRNA CASC19 Contributes to Radioresistance of Nasopharyngeal Carcinoma by Promoting Autophagy via AMPK-mTOR PathwaySemantic proximity Read

The functions of Atg8-family proteins in autophagy and cancer: linked or unrelated?Semantic proximity Read

Investigating the Association between the Autophagy Markers LC3B, SQSTM1/p62, and DRAM and Autophagy-Related Genes in GliomaSemantic proximity Read

Differential expression of GABARAPs in GBM renders temozolomide sensitivity in a p53-dependent mannerSemantic proximity Read

Targeting autophagy in neuroblastomaSemantic proximity Read

MIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma.Semantic proximity Read

Autophagy-Related Beclin 1 and Head and Neck CancersSemantic proximity Read

EBV-LMP1 promotes radioresistance by inducing protective autophagy through BNIP3 in nasopharyngeal carcinomaSemantic proximity Read

Relationship of PI3K-Akt/mTOR/AMPK signaling pathway genetic mutation with efficacy and prognosis in nasopharyngeal carcinoma.Semantic proximity Read

The Oncogenic Role of HIF-1α/miR-182-5p/ZFP36L1 Signaling Pathway in Nasopharyngeal CarcinomaSemantic proximity Read

ANXA6 Contributes to Radioresistance by Promoting Autophagy via Inhibiting the PI3K/AKT/mTOR Signaling Pathway in Nasopharyngeal CarcinomaSemantic proximity Read