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Article

The functions of Atg8-family proteins in autophagy and cancer: linked or unrelated?

7 Apr 2020

Abstract excerpt

The Atg8-family proteins are subdivided into two subfamilies: the GABARAP and LC3 subfamilies. These proteins, which are major players of the autophagy pathway, present a conserved glycine in their C-terminus necessary for their association to the autophagosome membrane. This family of proteins present multiple roles from autophagy induction to autophagosome-lysosome fusion and have been described to play a role...

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PMID: 32255730
DOI: 10.1080/15548627.2020.1749367

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