Article

Altered DNA methylation pattern characterizes the peripheral immune cells of patients with autoimmune hepatitis

2021-07-05

Abstract excerpt

<h4>Objective</h4> AIH is a chronic liver disease of unknown aetiology with favourable response to immunosuppression. Little is known about the impact of methylation modifications on disease pathogenesis. <h4>Design</h4> 10 patients with AIH at diagnosis (time-point 1; tp1), 9 with primary biliary cholangitis (PBC) and 10 healthy controls (HC) were investigated. 8/10 AIH patients were also investigated following b...

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Literature Corpus work: dc21b275-3869-55e1-aabd-1a0391ed5cdc
DOI: 10.1101/2021.07.01.21259836

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