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Epigenetic Aspects and Prospects in Autoimmune Hepatitis

30 Jun 2022

Abstract excerpt

The observed risk of autoimmune hepatitis exceeds its genetic risk, and epigenetic factors that alter gene expression without changing nucleotide sequence may help explain the disparity. Key objectives of this review are to describe the epigenetic modifications that affect gene expression, discuss how they can affect autoimmune hepatitis, and indicate prospects for improved management. Multiple hypo-methylated...

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PMID: 35844554
DOI: 10.3389/fimmu.2022.921765

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