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Nuclear Respiratory Factor 1 drives hepatocellular carcinoma progression by forming a positive feedback loop with LPCAT1-ERK1/2-CREB axis

2022-11-02

Abstract excerpt

<h4>Background: </h4> Nuclear respiratory factor 1 (NRF1) is a transcription factor that participates in several kinds of tumor, but its role in hepatocellular carcinoma (HCC) remains elusive. This study aims to explore the role of NRF1 in HCC progression and investigate the underlying mechanisms. <h4>Methods: </h4> HCC transcriptome sequencing data from TCGA was analysed. Functional role of NRF1 on HCC cells was...

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Literature Corpus work
dc0ec9b4-832b-57c8-8eb6-3d151b199222
DOI
10.21203/rs.3.rs-2212280/v1
Open publication

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